Colts owner: Manning will be out "awhile"

By MICHAEL MAROT | September 8, 2011 | 11:00 AM EDT

FILE - In this Aug. 26, 2011, file photo, Indianapolis Colts quarterback Peyton Manning looks on from the sideline during the third quarter of an NFL preseason football game against the Green Bay Packers in Indianapolis. Manning will not play Sunday, Sept. 11, 2011, in the season opener at Houston, bringing an end to his streak of 227 consecutive starts, including the playoffs. The team said 38-year-old Kerry Collins will start against the Texans as Manning continues his long recovery from neck surgery in May.(AP Photo/AJ Mast, File)

INDIANAPOLIS (AP) — Colts owner Jim Irsay says in a Twitter post that Peyton Manning may miss more than just Sunday's game at Houston.

Irsay tweeted that Manning could be out "awhile." He did not provide a timetable for Manning's return.

The tweet reads: "We had a good practice yesterday and r guys r fired up 4 the season. (hash)18's out for awhile, but compete, we will/BELIEVE."

Manning has already been ruled out of Sunday's season-opener, ending his streak of 227 consecutive starts including the playoffs. The streak is the second-longest among quarterbacks in NFL history, behind only Brett Favre.

The big question is when the only four-time MVP in league history will return.